What is a bladder cancer molecular subtype?
نویسندگان
چکیده
BACKGROUND: Several molecular classification systems for bladder cancer have been proposed, but due to differences on how define subtypes, controversies and misunderstandings arisen. OBJECTIVE: To discuss different aspects of the point consequences using conceptual approaches. question some underlying assumptions when defining subtypes. METHODS: critically reflect principles methods used RESULTS: Depending aims definitions types subtypes will be arrived at. CONCLUSION: The their must better clarified
منابع مشابه
What is new in bladder cancer imaging.
Treatment and prognosis of urinary bladder cancer largely are determined by the tumor stage and presence of metastases. MR imaging and clinical staging complement each other. MR imaging is the most accurate technique for differentiating the various stages of deep tumor infiltration and detection of metastases, whereas clinical staging is the best technique for differentiating between postbiopsy...
متن کاملWhat we could do now: molecular pathology of bladder cancer.
There is much information on the genetic alterations that contribute to the development of bladder cancer. Because it is hypothesised that the genotype of the cancer cell plays a major role in determining phenotype, this genetic information should impact on clinical practice. To date however, this has not happened. Some of the alterations identified in bladder cancer have clear associations wit...
متن کاملP-value: What is and what is not
The misinterpretation and misuse of p-value have been increasing for decades. In March 2016, the American Statistical Association released a statement to warn about the use and interpretation of p-value. In this study, we provided a definition and discussion of p-value and emphasized the importance of its accurate interpretation.
متن کاملMatrix Metalloproteinases and Bladder Cancer: What is New?
Urothelial bladder cancer represents a heterogeneous disease with divergent pathways of tumorigenesis. Tumor invasion and progression are a multifactorial process promoted by microenvironmental changes that include overexpression of matrix metalloproteinases (MMPs). Recent data clearly challenge the classic dogma that MMPs promote metastasis only by modulating the remodeling of extracellular ma...
متن کاملWhat Is Applied Literature?
Applied literature is a term that is the outcome of a need to put literature to tangible uses in the “real” world. A medical practitioner looking for a definition of life, for instance, finds literature a useful source for the answer. With paradigm shifts in scientific studies, interdisciplinarity has been a method to overcome the alienations that resulted from the isolation of disciplines from...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bladder cancer
سال: 2023
ISSN: ['2352-3727', '2352-3735']
DOI: https://doi.org/10.3233/blc-220124